Modeling COPD Immunopathogenesis Using Human Airway Organoid Systems and Immune Co-culture Systems

Principal Investigator

Dr. Anubama Rajan

Brief Summary of Project

This project proposes to model COPD immunopathogenesis using advanced and combined human airway organoid systems with immune cells, specifically focusing on the inflammatory response to inhaled particles, pollutants, and infectious agents. By integrating nCB exposure and RSV infection in the human airway organoid model, the project aims to unravel the complex interplay of environmental and biological factors contributing to COPD pathogenesis.