Engineering Patient-Specific Airway Organoids for Precision Medicine
Engineering Patient-Specific Airway Organoids for Precision MedicinePrincipal Investigator Dr. Anubama RajanBrief Summary of Project We are developing personalized airway organoids to model disease progression in response to environmental exposures, infections, and...
Linking COPD to Lung Cancer Progression
Linking COPD to Lung Cancer ProgressionPrincipal Investigator Dr. Anubama RajanChronic inflammation and impaired repair mechanisms in COPD create a high-risk environment for lung cancer development. This study utilizes spatial transcriptomics and organoid models to...
Understanding RSV’s Role in Lung Health
Understanding RSV’s Role in Lung HealthPrincipal Investigator Dr. Anubama RajanBrief Summary of Project This project explores how early-life Respiratory Syncytial Virus (RSV) infections impact lung development and contribute to chronic respiratory diseases like...
Regenerating the Pancreas: Stem Cell Innovations for Diabetes Therapy
Regenerating the Pancreas: Stem Cell Innovations for Diabetes TherapyPrincipal Investigator Dr. Anubama RajanBrief Summary of Project At ORGAMED Lab, IIT Madras, we are pioneering next-generation regenerative therapies for insulin-deficient diabetes using...
Therapeutic Interventions for COPD: Strategies Targeting Early Diagnostic Biomarkers and Immunotherapies
Therapeutic Interventions for COPD: Strategies Targeting Early Diagnostic Biomarkers and ImmunotherapiesPrincipal Investigator Dr. Anubama RajanBrief Summary of Project This project aims to identify potential therapeutic targets and interventions for COPD by...
Modeling COPD Immunopathogenesis Using Human Airway Organoid Systems and Immune Co-culture Systems
Modeling COPD Immunopathogenesis Using Human Airway Organoid Systems and Immune Co-culture SystemsPrincipal Investigator Dr. Anubama RajanBrief Summary of Project This project proposes to model COPD immunopathogenesis using advanced and combined human airway...
NCB induced Epithelial Damage in COPD
Investigating the Mechanisms of Nanocarbon Black-Induced Epithelial Damage in COPDPrincipal Investigator Dr. Anubama RajanBrief Summary of Project This project aims to evaluate how nanocarbon black (nCB) induces epithelial damage in a human nose organoid (HNO)...
Role of nCB and RSV in Acute Exacerbation of Airway Inflammation
Elucidating the Role of nCB and RSV in Acute Exacerbation of Airway InflammationPrincipal Investigator Dr. Anubama RajanBrief Summary of Project This project seeks to examine the concurrent effects of nanocarbon black (nCB) exposure and respiratory syncytial virus...
Mechanisms of Nanocarbon Black and RSV mediated inflammation in COPD using human airway Organoid model.
Mechanisms of Nanocarbon Black and RSV mediated inflammation in COPD using Human Airway Organoid Model.[dipl_lottie _builder_version="4.26.1" _module_preset="default" theme_builder_area="post_content" title_text="nCB-RSV-Research1"...